About Us
Founded in 1944, the American Committee for the Weizmann Institute of Science develops philanthropic support for the Weizmann Institute in Israel, and advances its mission of science for the benefit of humanity.
https://weizmann-usa.org/news-media/news-releases/predicting-immunotherapy-success/
Feb 18, 2020... REHOVOT, ISRAEL—February 18, 2020—One of the frustrations with anti-cancer therapy is that no one drug fits all: Most work well in some people but have little effect in other patients with the same type of cancer. This is as true of the newer immunotherapy treatments as it is of older types of chemotherapy. Weizmann Institute of Science researchers have now identified new markers that can help predict which patients have a better chance for a positive response to immunotherapy treatments. Their findings were reported in Nature Communications.
Feb 25, 2020...
After investing $26 million in research during the past 15 years, NETRF has helped to establish the NET knowledge base needed to expand the exploration of improved treatments, according to Elyse Gellerman, NETRF Chief Executive Officer. “We can see real momentum in this new round of grants. We hope the discoveries from these projects will lead to improved treatment options for patients.”
NETRF is supporting a new pioneering approach to NET immunotherapy with a Petersen Accelerator Award to Steven Libutti, MD, Rutgers Cancer Institute of New Jersey, to characterize a novel immune regulator called B7x to determine whether it has a role in shutting off the body’s immune response to fight against pancreatic NETs.
https://weizmann-usa.org/news-media/in-the-news/6-groundbreaking-breakthroughs-in-melanoma-research/
May 14, 2020...
May is Skin Cancer Awareness Month. And one important fact to be aware of is that the most common skin cancers, basal cell carcinoma and squamous cell carcinoma, aren’t the ones that kill.
The least common variety, melanoma, causes most skin-cancer deaths because it quickly spreads (metastasizes) to other parts of the body.
That’s why many researchers around the world focus on melanoma, so-called because it starts in melanocyte cells that give skin its color.
Jun 02, 2020... REHOVOT, ISRAEL—June 2, 2020—Cancer cells are comfy havens for bacteria. That conclusion arises from a rigorous study of over 1,000 tumor samples of different human cancers. The study, headed by researchers at the Weizmann Institute of Science, found bacteria living inside the cells of all the cancer types – from brain to bone to breast cancer – and even identified unique populations of bacteria residing in each type of cancer. The research suggests that understanding the relationship between a cancer cell and its “mini-microbiome” may help predict the potential effectiveness of certain treatments or may point, in the future, to ways of manipulating those bacteria to enhance the actions of anticancer treatments. The findings of this study were published in Science and featured on the cover.
May 28, 2020...
The first comprehensive survey of the microorganisms that live inside tumours has found that bacteria reside in those from many different cancer types, but it is unclear whether they contribute to tumour growth.
These bacteria make up part of a tumour’s microbiome – the complex community of bacteria, fungi and other microbes that live inside it.
Bacteria have previously been found in tumours in the bowel and other tissues in the body that are routinely exposed to microbes. However, less is known about their presence in tumours from other cancers, like those of the bone, brain and ovary.
Jul 16, 2020... REHOVOT, ISRAEL—July 16, 2020—Choosing the right drug for each cancer patient is key to successful treatment, but physicians currently have few reliable pointers to guide them in designing treatment protocols. Researchers at the Weizmann Institute of Science and the Broad Institute of MIT and Harvard have now developed a new method for selecting the best drug therapy for a given tumor, based on assigning scores to the cells’ internal messaging activities. In addition to helping physicians choose from a list of existing treatments, the method can help identify new molecular targets for the development of future drugs. In fact, the researchers have already used it to single out a gene that can be targeted for effectively treating breast cancers with a BRCA mutation. The study was recently published in Nature Communications.
Sep 04, 2020...
Blood cancers are far too common, comprising almost 10% of new cancer diagnoses each year in the U.S. Almost every 10 minutes, an American succumbs to a blood cancer. Unfortunately, many of these are children.
That's why the Weizmann Institute of Science’s researchers are conducting innovative studies and taking novel approaches to blood cancers. September is Blood Cancer Awareness Month, and we’d like to share with you some of Weizmann’s current investigations.
Oct 06, 2020...
October is National Breast Cancer Awareness Month, a time that is typically packed with runs, walks, and other events. While this year is different due to the coronavirus, stepping up to support and advance the science is as important as ever.
Breast cancer research is actively underway at the Weizmann Institute of Science, with researchers applying their formidable skills to improve understanding, diagnosis, and treatment of this still-too-common disease. Working in collaboration with oncologists and other medical professionals around the world, Institute scientists are continually making groundbreaking progress, demonstrating the role that curiosity-driven, interdisciplinary science plays in the battle against breast cancer. Just a few of the innovative projects taking place right now include:
https://weizmann-usa.org/news-media/in-the-news/the-cell-whisperer/
Nov 21, 2020... These are coronavirus days, and very few people can be seen in the narrow corridors of the Weizmann Institute of Science in Rehovot. We’re in the molecular immunology laboratory, located in one of the institute’s old buildings. It’s a simple place, the instruments are banal and dull. It looks like any lab in the world, one of thousands. But a miracle is occurring between the walls here. In the small details. The smallest.
Dec 16, 2020... REHOVOT, ISRAEL—December 16, 2020—Cancers like melanoma are hard to treat, not least because they have a varied bag of tricks for defeating or evading treatments. Now, a combined research effort by the Weizmann Institute of Science, the Netherlands Cancer Institute in Amsterdam, and the University of Oslo shows exactly how tumors, in their fight to survive, will go so far as to starve themselves in order to keep the immune cells that would eradicate them from functioning. The work was published in Nature.
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